Toxicity testing Essay Example | Topics and Well Written Essays - 250 words - 1

Toxicity testing - Essay Example Thus, chronic testing extends over a longer period than the sub chronic testing. The observation period for sub chronic testing is about three months, while the observation period for chronic testing is about twelve to twenty-four months (Hamilton, 1977). Sub chronic testing usually involves lesser group of animals than chronic testing. While chronic testing could involve a large group of animals of about twenty for each sex (for rodents), sub chronic testing could take about ten for each sex (for rodents) (Hamilton, 1977). The name sub chronic testing is even an indicator that it involves a lower level of toxicity testing o the chronic testing. In carrying out the toxicity experiment, there are several factors that should be considered in order to determine the most suitable toxicity method. It should be noted that, if a large group of animals is involved, the chronic testing method is preferred, but if it is only a few group of animals, the sub chronic testing method is preferred over the chronic testing